Alzheimer's Disease
It is a developing brain disease that slowly does away with memory and thinking skills results in confusion, disorientation, reason, understanding, and eventually leading up to the inability to perform the most basic tasks of daily living. Alzheimer's disease is the most common cause of dementia among older people.
The disease is named after Dr. Alois Alzheimer a german psychiatrist and neuropathologist who was the first to publish a case of "presenile dementia" which would later be known as Alzheimer's Disease.
What is Dementia??
The loss of cognitive functioning; thinking, remembering, reasoning, and behavior abilities.
Dementia is cause by many conditions and diseases but the two most common cause for dementia in older people are Alzheimer's disease and vascular dementia.
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Memory loss or dementia may also be caused by:
- medication side effects
- chronic alcoholism
- tumors or infections in the brain
- blood clots in the brain
- vitamin B12 deficiency
- thyroid, kidney, or liver disorders
What happens to the Brain??
Alzheimer's disease comes into the brain like a thief, there is no specific knowledge of how the disease begins until there is significant evidence that could have started a decade or more before. Even though the person is asymptomatic at the early stage of Alzheimer's there is toxic changes taking place in the brain. Alzheimer's disease causes abnormal deposits of proteins from amyloid plaques and tau tangles on both the inside and outside neurons while damage dendritic spines, decrease synaptic input, and decrease plasticity. As the plaques accumulates the damages spreads to the cerebral cortex and hippocampus, which is responsible for forming memories. As the neurons die in large numbers the affected regions of the brain begin to shrink.
Early signs and symptoms
Memory problems, such as trouble finding the correct words or poor judgment.
Mild Alzheimer's disease
Memory loss worsens and cognitive abilities are significant:
- getting lost
- trouble handling money and paying bills
- repeating questions
- taking longer to complete normal daily tasks
- poor judgement
- losing things - misplacing things in odd places
- mood and personality changes
At this point the damage done to the brain affects language, reasoning, sensory processing, and conscious thoughts.
- increase memory loss and confusion
- problem recognizing familiar faces
- inability to learn new things
- unable to multitask
- problems coping with new situations
- hallucinations, delusions, and paranoia
- impulsive behavior
Once Alzheimer's is full blown the person is no longer able to communicate and is completely dependent on others and may be bedridden.
- unable to communicate
- weight loss
- seizures
- skin infections
- difficulty
- groaning, moaning, or grunting
- sleeps most of the time
- uncontrolled bladder and bowel
I read somewhere that when we die we should have our memory intact. I find it interesting how Alzheimer's disease can't be diagnosed with no specific medical exam other than ruling out all possible medical conditions or family medical history. Not only does it affect the patient with Alzheimer's but his/her family as caregivers'. It must be very overwhelming and stressful depending on the severity of the disease. I hope that one day we acquire more knowledge in research to help and prevent this deliberating disease.
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